Which NSAID is explicitly associated with higher GI bleed risk and AKI and should be avoided?

Study for the AGS Beers Criteria Test. Prepare with flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam with comprehensive resources!

Multiple Choice

Which NSAID is explicitly associated with higher GI bleed risk and AKI and should be avoided?

Explanation:
Ketorolac is the NSAID most strongly linked to both gastrointestinal bleeding and acute kidney injury, so it is the one to avoid, especially in older adults or those with CKD or high GI risk. It’s a potent NSAID, and while other NSAIDs like ibuprofen, naproxen, and diclofenac also carry GI and kidney risks, ketorolac has the strongest association and is typically reserved for very short-term inpatient use when alternatives are not suitable. This is why it’s singled out as the drug to avoid in the Beers Criteria contexts.

Ketorolac is the NSAID most strongly linked to both gastrointestinal bleeding and acute kidney injury, so it is the one to avoid, especially in older adults or those with CKD or high GI risk. It’s a potent NSAID, and while other NSAIDs like ibuprofen, naproxen, and diclofenac also carry GI and kidney risks, ketorolac has the strongest association and is typically reserved for very short-term inpatient use when alternatives are not suitable. This is why it’s singled out as the drug to avoid in the Beers Criteria contexts.

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